An example of a major city that is located in an unfavorable location would be:

A major city would be Mexico City

Ibelieve the answer is c

So  if  the sum of the enthalpies of the reactants is greater than the products, the  reaction  will be  exothermic.  if  the products side has a larger enthalpy, the  reaction  is  endothermic. you may wonder why  endothermic reactions, which soak up energy or enthalpy from the environment, even happen