Who threatened the land trade routes to the far east? turks spanish indians africans

There were a lot of factors why the land trade routes were threatened to the Far East, but the major reason why trade in the Far East was disrupted was because of the Turks. During the year 1453, trade stopped. This was because the Turks from the Ottoman Empire took over Constantinople. When they invaded Constantinople, control in the Middle East became theirs. Because of this invasion, goods from places such as Asia became scares.