Most homeostatic regulation is controlled by the release of hormones (endocrine system) into the bloodstream (circulatory). However, other regulatory processes rely on simple diffusion to maintain a balance.
Homeostatic regulation extends far beyond the control of temperature (this would a combination of.the circulatory system and the skeletal muscle system) All animals also regulate their blood glucose, as well as the concentration of their blood (the circulatory, excretory, and endocrine systems all work together to accomplish this). Mammals regulate their blood glucose with insulin and glucagon. The human body maintains glucose levels constant most of the day, even after a 24-hour fast. Even during long periods of fasting, glucose levels are reduced only very slightly. Insulin, secreted by the beta cells of the pancreas, transports glucose to the body's cells, lowering blood glucose levels. Insulin helps to prevent hyperglycemia. When insulin is deficient or cells become resistant to it, diabetes occurs. Glucagon, secreted by the alpha cells of the pancreas, helps the body utilise stored glycogen or convert non-carbohydrate carbon sources to glucose via gluconeogenesis, thus preventing hypoglycemia. The kidneys are used to remove excess water and ions from the blood. These are then expelled as urine. The kidneys perform a vital role in homeostatic regulation in mammals, removing excess water, salt, and urea from the blood. These are the body's main waste products.
Sleep timing depends upon a balance between homeostatic sleep propensity, the need for sleep as a function of the amount of time elapsed since the last adequate sleep episode, and circadian rhythms that determine the ideal timing of a correctly structured and restorative sleep episode
The endocrine system is a system of glands, each of which secretes a type of hormone to regulate the body. The field of study that deals with disorders of endocrine glands is endocrinology, a branch of the wider field of internal medicine. The endocrine system is an information signal system much like the nervous system. Hormones regulate many functions of an organism, including mood, growth and development, tissue function, and metabolism.
The circulatory system is an organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. This system may be seen strictly as a blood distribution network, but some consider the circulatory system as composed of the cardiovascular system, which distributes blood, and the lymphatic system, which distributes lymph. While humans, as well as other vertebrates, have a closed cardiovascular system (meaning that the blood never leaves the network of arteries, veins and capillaries), some invertebrate groups have an open cardiovascular system.
The excretory system is a biological system that removes excess, unnecessary or dangerous materials from an organism. It is responsible for the elimination of oxygen waste products of metabolism as well as other nitrogeneous materials. Since the normal operation of most biological systems creates waste, the excretory system is not necessarily distinct from other systems. Instead, it often represents the various excretory processes of several different systems
The skin is another part of the excretory system: it releases sweat, which helps cool the body and regulate the concentration of salt. The salt helps the water evaporate, cooling off the skin.
The liver is an organ of the digestive system. It also helps in excreting wastes from the body in a variety of processes. Laboratory analysis reveals a high concentration of a small organelle called a peroxisome, responsible for breakdown of several toxic substances. It also takes in nitrogenous wastes and converts them to urea to reduce their toxicity.
In anatomy, the urinary bladder is the organ that collects urine excreted by the kidneys prior to disposal by urination. A hollow muscular, and distensible (or elastic) organ, the bladder sits on the pelvic floor. Urine enters the bladder via the ureters and exits via the urethra.
