Why does the story in the video start in columbia? why does the story in the video start in columbia? there is an extended family with inherited early onset alzheimer's in columbia, and family members with the gene can be participants in a drug trial to reduce plaques. there is an extended family with early onset alzheimer's in columbia, and researchers want to determine what environmental factor is causing it. there are no cases of inherited early onset alzheimer's in columbia, and researchers want to know what protects the population. there is an extended family with inherited alzheimer's in columbia, and researchers want to find the gene that causes it?