How do enzymes make chemical reactions more efficient

By lowering energy of activation of the reaction.

High energy produced during the metabolism of reactant to product. Due to the large free energy of activation, the speeds of uncatalyzed biochemical reactions are often exceedingly slow. Enzymes lower this energy of activation so that more molecules have adequate energy to carry into the transition state to speed up the rate of reaction.

answer >   yes we do, women; have three holes, urethral opening(pee hole, vagina, and the women pee/girls pee out of the urethra like the men do; only they have a single opening to pee/ejaculate.   (sorry if i'm too forward with this, but this is for a biology class, isn't it? )

hope that !         : )