The shape of a protein molecule directly determines (1) movements through the cytoplasm (2) functions inside and outside of cells (3) roles in building water molecules (4) circulation throughout the body !

The right answer is (2)

The proteins fold on themselves to adopt a unique native 3-D structure that gives them their biological properties.

Proteins are organized into domains: they are functional and / or structural units distinct from proteins. They are usually responsible for a particular function or interaction and contribute to the function of the protein.

helicase, i think thats it