Which of the following will pass through a cell membrane most easily? a) small polar molecules b) small nonpolar molecules c) large polar molecules d) large nonpolar molecules e) large neutral molecules

B) small non-polar molecules. Small molecules can pass through the cell membrane through diffusion (does not require energy). The molecule being non-polar is an advantage because the tails of the phospholipid bilayer is hydrophobic (nonpolar), so it does not repel nonpolar molecules.

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