What aligns and segregates during meiosis i? what aligns and segregates during meiosis ii? in what way is prophase i of meiosis similar to prophase of mitosis? how is it different? in what way is metaphase i of meiosis similar to metaphase in mitosis? how is it different? which is more similar to mitosis (meiosis l or meiosis ii)? what is the important similarity? what is the significance of meiosis in terms of the genetic content of the cells produced? in terms of the genetic makeup of the whole species? what are two features of meiosis that result in the production of genetically distinct gametes?