Which of the following statements regarding the chemical mediators of inflammatory responses is not true? a. they may be secreted by cells residing in the area of injury. b. they may be secreted by cells that enter the affected area. c. they may be generated by enzymatic cleavage of proteins in plasma. d. they are all peptides. e. they may be chemotaxins.

The correct answer is: D. They are all peptides.

Mediators of inflammation released by certain type of cell have a function to control the later accumulation and activation of other cells. Chemical mediators of inflammatory responses are soluble, diffusible molecules that can act locally (at the site of tissue damage / infection) or at distant sites. These mediators include vasoactive amines and peptides, eicosanoids, proinflammatory cytokines. They respond to  inflammatory process by preventing further tissue damage and ultimately resulting in restoration of tissue function.