Which of the following is an example of cooperativity?
a) the binding of an end product of a metabolic pathway to the first enzyme that acts in the pathway
b) one enzyme in a metabolic pathway passing its product to act as a substrate for the next enzyme in the pathway
c) a molecule binding at one unit of a tetramer, allowing faster binding at each of the other three
d) binding of an atp molecule along with one of the substrate molecules in an active site

The correct answer is: C) a molecule binding at one unit of a tetramer, allowing faster binding at each of the other three

The phenomenon called cooperativity occurs when the binding of a substrate molecule to the first active site of an enzyme may in¬fluence substrate binding to a second active site.Binding of the second then influence binding of a third, and so on.  

Cooperativity can be positive or negative:

•Positive- the first molecule facilitates binding of sub-sequent molecules  

•Negative- binding of a  subsequent molecule is reduced by the binding of the first one.

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