Results from gene mutations in cells which cause uncontrolled cell division

Occasionally mutations result in a different protein being formed that gives the cell or organism an advantage in a particular environment. Sometimes mutations cause problems – these may be in the form of a change that causes a genetic disease or they may result in the uncontrolled cell growth we recognise as cancer.

Explanation:

https://www.abpischools.org.uk/topic/celldivision/5

the solute can move "downhill," from regions of higher to lower concentration, relying on the specificity of the protein carrier to pass through the membrane. this process is called passive transport or facilitated diffusion, and does not require energy.