Cas9 cleaves both strands of the target dna. which of the following could occur when cells will try to repair the damage after cleavage by cas9? (select all that apply)
a. the insertion of a dna sequence into the targeted gene
b. mutations that result in changes to the open reading frame (orf) of the targeted gene.
c. deletions of the targeted gene
d. loss-of-function mutations within the targeted gene
e. no change in the targeted gene