Which of the following resistance mechanisms is the most nonspecific to a particular class of antimicrobials?
drug modification
target mimicry
target modification
efflux pump

The efflux pump is the most nonspecific to a particular class of antimicrobials.

Explanation:

Antimicrobial -

An antimicrobial , the agent which destroys or kills the microorganism or inhibits their growth .

And these microbes can even develop resistance mechanism which involves the inhibiting the accumulation of the antimicrobial drug .

This is very common among the gram - negative pathogens and hence , involve changes in the outer lipid membrane composition , porin channel concentration and porin channel selectivity .

The gram - negative and gram - positive pathogens bacteria produces efflux pumps that can actively transport the drug out of the cell and thereby prevents the accumulation of the the drug .

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