Why is it more common for doctors to recommend amniocentesis and cvs for women over the age of 35?

The age of 35 years was established to offer invasive techniques, because at this age the risk of secondary abortion was balanced by the technique and the risk of chromosomal alteration.

Explanation:

The possibility of early diagnosis of fetal anomalies of various kinds (neural defects, chromosomopathies, etc.) has been one of the top concerns of gynecologists and geneticists, for obvious reasons.

Throughout these years, prenatal diagnostic techniques have been developed that allow therapeutic decisions by doctors or viability of pregnancy by parents. These techniques are initially performed with non-invasive methods (biochemical determinations, ultrasound), and if the suspicion is increasing, it is passed to more invasive techniques such as amniocentesis or chorionic villus biopsy.

Given that in the latter there is a risk of loss of pregnancy, it is previously attempted to ensure that the indication is correct, and for this, new biochemical tests and risk calculation systems have been added.

Until recently the criterion for establishing the risk of fetal chromosomal abnormality was the mother's age, since there was a clear relationship between maternal age and chromosomal abnormalities, especially Down. The age of 35 years was established to offer invasive techniques, because at this age the risk of secondary abortion was balanced by the technique and the risk of chromosomal alteration. The problem was that a small number of cases were detected. Therefore, other parameters have been sought that estimate more precisely those subsidiary chaos of early detection.

The estimation of the risk in a given pregnant woman is done by multiplying the risk associated with her age for the specific gestational age.

Currently, most prenatal tests consist of AFP, estriol and human chorionic gonadotropin (hCG), which is the triple test, which is a blood test that assesses the risk in a pregnancy of having a Down syndrome or spina bifida It is not a test that tells us whether or not the fetus has any of these defects. It is a test that tells us the probability of risk of having them. Studies have shown that about 70% of fetuses with Down syndrome can be identified early combining the analysis of the mother's age and the results of the triple test.

interphase   is the cell cycle stage in which the cell acquires nutrients, creates and uses proteins and other molecules and starts the process of cell division by replicating the dna. it is the longest stage in the eukaryote cell cycle.

the following   can go wrong during interphase:   a base pair could be mismatched during the duplication process causing a mutation.   correct answer: c

explanation:

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