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Biology, 02.11.2019 05:31 SmokeyRN

Arsenate (aso43-) closely resembles pi in structure and reactivity. in the reaction catalyzed by glyceraldehyde 3-phosphate dehydrogenase, arsenate can replace phosphate in attacking the energy-rich thioester intermediate. the product of this reaction, 1-arseno- 3-phosphoglycerate, is unstable. it and other acyl arsenates are rapidly and spontaneously hydrolyzed. what is the effect of arsenate on energy generation in a cell?

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