Acouple has seven children, three of whom have cystic fibrosis (cf), a recessive trait. the first son (ii-1) would like to know if there is a chance that he is a carrier for cystic fibrosis. geneticists used three microsatellite markers, 1.2 and 3 to analyze the dna of the family. all three markers are already known to be extremely closely linked to, or within, the cf gene. the alleles are labeled a, b and c to the left of the gel. based on this data: a) do we expect there to be recombination among the various markers and the cf gene? b) draw the chromosomes of the mother and father and of one affected child. be sure to indicate the phase of linkage of each marker and the cf disease allele. do not worry about the ordering of the markers and cf gene on the chromosome. c) is the man (ii-1) a carrier of cystic fibrosis? d) which of his siblings is not a carrier for cystic fibrosis? e) which marker is not informative and why? marker 1 b, c a, c a, c marker 2 marker 3 genetic 7 marker
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Acouple has seven children, three of whom have cystic fibrosis (cf), a recessive trait. the first so...
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