Which system coordinates the body’s response to changes in its internal and external environment?

lymphatic system
nervous system
excretory system
reproductive system

The Nervous System recognizes and coordinates the body’s response to changes in its internal and external environments. The lymphatic system helps protect the body from disease. The excretory system eliminates waste products from our body in ways that maintain homeostasis. And the reproductive system as we all know produces reproductive cells.

Nervous System

I hope it helps, Regards.