Consider the hiv enzyme called protease. the amino acid residues at the active site are highly hydrophobic. in designing a drug that would bind to the active site and jam it, researchers should use which type of molecule?
a. charged
b. polar
c. hydrophobic
d. acidic

c. hydrophobic

Explanation:

Hydrophobic domains will aggregate. Hence another hydrophobic substance will like to be together with the hydrophobic active site. The active site is an enzyme region where the molecules of substrates bind and undergo a chemical reaction. The active site consists of residues which form temporary substratum bonds (binding site) and residues that catalyze a substratum reaction (catalytic site)

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explanation: