What happens if p53 is mutated?

Most TP53 mutations change single amino acids in the p53 protein, which leads to the production of an altered version of the protein that cannot control cell proliferation and is unable to trigger apoptosis in cells with mutated or damaged DNA. As a result, DNA damage can accumulate in cells

the main thing i would use is bricks because if there is a hurricane, there is a great possibility for the house to still stand. and i would also use plexiglass windows instead of regular windows because plexiglass isn't prone to breaking.