Imagine that a newly discovered, recessively inherited disease is expressed only in individuals with type o blood, although the disease and blood group are independently inherited.
a normal man with type a blood and a normal woman with type b blood have already had one child with the disease. the woman is now pregnant for a second time.
assuming that both parents are heterozygous for the gene that causes the disease, what is the probability that the second child will also have the disease? express your answer as a fraction using the slash symbol and no spaces (for example, 1/2).

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explanation:

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fertilization, pictured in figure 24.23a is the process in which gametes (an egg and sperm) fuse to form a zygote. the egg and sperm each contain one set of chromosomes. to ensure that the offspring has only one complete diploid set of chromosomes, only one sperm must fuse with one egg. in mammals, the egg is protected by a layer of extracellular matrix consisting mainly of glycoproteins called the zona pellucida. when a sperm binds to the zona pellucida, a series of biochemical events, called the acrosomal reactions, take place. in placental mammals, the acrosome contains digestive enzymes that initiate the degradation of the glycoprotein matrix protecting the egg and allowing the sperm plasma membrane to fuse with the egg plasma membrane, as illustrated in figure 24.23b. the fusion of these two membranes creates an opening through which the sperm nucleus is transferred into the ovum. the nuclear membranes of the egg and sperm break down and the two haploid genomes condense to form a diploid genome.

explanation:

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