Up-regulation involves the loss of receptors and prevents the target cells from overreacting to persistently high hormone levels. up-regulation involves the loss of receptors and prevents the target cells from overreacting to persistently high hormone levels. true false

False

Explanation:

Downregulation is a decrease in the receptors number on the surface of the target cells and make the cells less sensitive to external stimuli or hormone. An example is in type 2 diabetes wherein the insulin receptors can be downregulated. The self-induced loss of target cells receptors for insulin reduces the target cell's sensitivity to the elevated hormone concentration.

False

Explanation:

Down-regulation involves the loss of receptors and prevents the target cells from overreacting to persistently high hormone levels.