If you wished to control chronic high blood pressure in a person, which hormones should you block? assume that this individual exhibits no signs of emotional stress.

The prime three hormones that play the primary role in hypertension are cortisol, angiotensin II and aldosterone. Cortisol is also termed as the stress hormone, however, in the given case the individual shows no sign of emotional stress. As cortisol is produced mainly at the time of stress, therefore, blocking the hormone would not be a point.  

Angiotensin II possesses the tendency to constrict the blood vessels, and thus, enhances the blood pressure, and at the same time instigates the generation of aldosterone. Aldosterone leads to the recaptivation of sodium in the distal convoluted tubule. This enhanced reabsorption of sodium is succeeded by chloride and water, which further increases blood pressure.  

Thus, blocking angiotensin II and aldosterone may play a significant role in monitoring blood pressure.  

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