3.3 - explain how mutations in the dna sequence of a gene may or may not result in phenotypic change in an organism. explain how mutations in gametes may result in phenotypic changes in offspring. a certain genetic disorder is caused by a single base mutation in the dna of a certain gene. the mutation changes the amino acid glutamate (glu) to aspartate (asp).

identify the type of macromolecule (carbohydrate, lipid, nucleic acid, protein) that changes when glu changes to asp. explain your answer.

a portion of the amino acid sequence that includes this mutation is shown below.

val-ser-ala-arg-asp

the sample of dna below is being analyzed to determine if a patient has the genetic disorder.

3’  caa-tcg-cgg-tct-ctt  5’

determine the mrna sequence from the patient's dna sequence.

using the information in the codon table below, determine the amino acid sequence that is coded for by the mrna sequence you determined in part (b).

determine whether the patient has the genetic disorder. explain your answer.