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Sidney brenner argued that the code was nonoverlapping because he considered that coding restrictions would occur if it were overlapping. a second major argument against an overlapping code involved the effect of a single nucleotide change. in an overlapping code adjacent amino acids would be affected by a point mutation, while in a nonoverlapping code amino acid(s) would be affected.
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Sidney brenner argued that the code was nonoverlapping because he considered that coding restriction...
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