Which of the following summarizes the overall climate of earth over time?

earth’s climate was unchanging until 50 years ago.
earth’s climate has warmed and cooled at different times.
earth’s climate has gotten consistently warmer over time.
earth’s climate does not change over time.

Earth's climate has gotten consistently warmer over time.

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answer: b. nucleolus

explanation: nucleolus is a structure in the nucleus are ribosomes are made.

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osteogenesis imperfecta (oi) refers to a congenital ailment of bones. in the condition, the bones become brittle or fragile. this ailment is a general result of the defect or mutations in the genes (colia1 or colia2). this mutation results in imperfect collagen formation either in quantity or quality wise.  

there are eight kinds of oi defects, and each kind varies with certain distinctions in symptoms. the usual symptoms include frequent bone fractures, loss of hearing in infants, protruding eyes, discoloration of the white in the eyes, respiratory issues, loosening of the joints, short stature, and other symptoms.