What advantage is there to phosphoglycerate kinase having an open and closed configuration?

question 7 options:

none of these answers are correct.

the induced-fit mechanism maximizes accessibility of active site without sacrificing hydrophobic environment.

it allows water to be trapped in the active site along with the substrate.

changing of the configuration of the enzyme makes the reaction exergonic.

it forces covalent binding of the substrate to the enzyme active site.

The correct answer is "The induced-fit mechanism maximizes accessibility of active site without sacrificing hydrophobic environment".

Explanation:

Phosphoglycerate kinase is an enzyme that participates in a step of glycolysis by transferring a phosphate group from 1,3-bisphosphoglycerate (1,3-BPG) to ADP, generating the following intermediary compound and a molecule of ATP. The phosphoglycerate kinase has an open and closed configuration, which has the advantage that the induced-fit mechanism maximizes accessibility of active site without sacrificing hydrophobic environment. This help the enzyme to have a more stable configuration and regulates its use in glycolysis.

for  example, forests have higher evapotranspiration than other ecosystems,  such  as grasslands, because of their deeper roots and greater leaf area. thus forests have a net moistening effect on the atmosphere and become a moisture source for downwind ecosystems.