Ketone bodies, the byproduct of fat metabolism, if found in the urine can be indicative of what life threatening disorder?

uncontrolled 1 diabetes mellitus.

Explanation:

Keto bodies elevation of the urine is due to:

1.non availability of glucose in the blood to be used by the cells for biochemical activities,

OR

GLUCOSE can not enter cells because of absence of INSULIN hormone which moderate GLUT TRANSPORTERS 1 and 4 for entry of glucose into cells in induvidual with Type 1 diabetes.

TYPE 1 diabetes is a condition where the pancreas beta cells refused to secret hormone insulin,therefore affecting the entry of glucose into cells. Leading to elevated blood glucose level,and loss in the urine (Hypoglycemia from polyuria(too much urination.)Because the primary function of insulin is to facilitate the uptake of glucose into cells.

In this induvidual the liver converted excess tryglycerides to glucose in a process called GLUCONEOGENESIS(. The prouction of glucose from non carbohydrate compounds.)

The metabolized lipids leads to build up of byproduct ketone bodies in the blood.This produce ketosis and later progress to Ketoacidosis or metabolic acidosis

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