Macrophage cells undergo a process called phagocytosis in which material is brought into a cell in the form of membrane vesicles and then transported along microtubules toward the cell center. assuming that the centrosome is near the cell center, you can predict that these vesicles are moving to the end of microtubules using the motor protein

Minus and dyenin.

Explanation:

The cell skeleton or cytoskeleton helps in the movement of the cell organelles and plays an important role during cell division. Three main types of cytoskeleton are microtubules, microfilaments and intermediate filament.  

The microtubule is made of the tubulin polymer that has the polrity at the two ends. The two main proteins present in microtubules are kinesin and dyenin. The vesicles that are near the center of the cell are moving to the minus end. The protein that helps in this movement is known as dyenin.

Thus, the answer is minus and dyenin.