The two major hormones secreted from the pancreas are: a. estrogen and progesterone b. norepinephrine and epinephrine c. thyroxine and oxytocin d. glucagon and insulin

option D) glucagon and insulin

Explanation:

The hormones glucagon and insulin are secreted by the islets cells found in the pancreas. Specifically, alpha cells of the islet produce glucagon, while its beta cells produce insulin.

Both hormones operate in opposite action, glucagon respond to low blood sugar levels while insulin respond to high blood sugar levels.