At the site of the rough endoplasmic reticulum, proteins that are destined for secretion are manufactured. Insulin is a protein-based hormone made by cells in the pancreas. Which type of vesicular transport is involved with the exporting of these protein-based hormones into the bloodstream?

The type of vesicular transport involved in the exporting of protein-based hormones, such as insulin, into the bloodstream is regulated exocytosis.

Explanation:

In general terms, exocytosis is a type of active transport that allows intracellular substances are released to the extracellular space, through of vesicles that fuse with the plasma membrane, which allow the exit of substances from inside the cell.

Regulated exocytosis is the specific vesicular transport for the secretion of substances, such as hormones. For this type of transport to exist, the presence of an extracellular signal is required, which will activate the fusion of the vesicles.

In the case of insulin, the external signal originates with the increase in blood glucose levels, a signal that penetrates the intracellular space and generates an increase in insulin production in the islets of Langerhans (pancreas).

Before insulin secretion occurs, the cell must be depolarized, allowing calcium to enter, which promotes transport by regulated exocytosis of insulin to the extracellular space.

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