Shelly is pessimistic about her future. Her disinterest for everything around her, together with worry and rumination, make it difficult for her to cope with even the most minor of daily events. These symptoms demonstrate which domain of depression?

cognitive

Explanation:

The symptoms of depression are characterized into three broad groups  

1.Cognitive – The common symptoms observed include constant negative thoughts, pessimism, feeling guilty for all bad happenings around them, thinking of ending their life

2.Behavioral – These include behavioral changes occurring in a person facing depression such as poor hygiene, inefficiency in work, constant crying, anti-social thoughts and behaviour and low energy

3.Emotional – Under this head a person feel sad, lonely, worthless and hopeless.

this protocol provides a detailed procedure for co-immunoprecipitation (co-ip) to identify protein–protein interactions.

cell regulation is conducted by special proteins.