Besides filtering blood for foreign materials and phagocytosis of old, defective erythrocytes, the spleen is also involved in what other major function?

Functions of spleen

Explanation:

The major functions of spleen besides filtering the blood of foreign materials and phagocytosis of old defective erythrocytes are:

Body defense: Initiate immune responses against infections by liberation of antigen and activation of lymphocytes (T and B cells)  Secretes bactericidal agents which act against invading bacteria Secretes interleukins which promote the growth of lymphocytes or antibodies that act against pathogens Reservoir: Pools blood by storing thrombocytes, immature erythrocytes. Hematopoiesis: Blood cells like erythrocytes, lymphocytes and monocytes develop and mature in spleen especially during the early fetal life.  

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