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Biology, 25.02.2020 00:07 hernandezramirp2pjmh
Researchers can manipulate the genes of a mouse so that a single gene in a single tissue either produces an inactive protein (a knockout mouse) or produces a protein that is always (constitutively) active. What effects on metabolism would you predict for mice with the following genetic changes?
Knockout of the FBPase-2 domain of PFK-2/FBPase-2 in the liver:
1) Effect on glucose metabolism:
2) Effect on glucose levels:
Constitutively active PFK-2 in the liver:
1) Effect on glucose metabolism:
2) Effect on glucose levels:
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