The mutation that causes sickle cell disease in humans is

Missense mutation

Explanation:

Missense mutation is a type of point mutation where a single nucleotide is changed to cause substitution of a different amino acid. This in turns render the resulting protein non-functional.

In the case of sickle-cell disease, the sixth amino acid in the gene sequence, glutamate (GAG) is substituted with valine (GUA), due to Adenine nucleotide changed to Uracil nucleotide. Thus, missense mutation has occurred

the answer is b)3/8x+1

i think its white blood cells

i hope this