Most eukaryotic genes are normally inactive and require positive regulation. Determine whether the situations described are associated with positive regulation (activation) or negative regulation of eukaryotic genes. If one of the choices is not a factor involved in regulating transcription or if a choice does not apply.

a. Susceptible to DNase
b. transactivator interacts with histone acetyltransferases (HATs)
c. mediator detaches from RNA polymerase II
d. coactivator bond to DNA
e. euchromatin
f. increased histone deacetylase activity