Amino acid-derived and peptide hormones are unable to diffuse across a cell membrane because they are .
a. large
b. too complex
c. lipid-based
d. not easily dissolved in blood
e. polar

Option E) polar

Amino acid-derived and peptide hormones are unable to diffuse across a cell membrane because they are polar

Explanation:

Amino acid-derived and peptide hormones such as serotonin, epinephrine, dopamine etc, are unable to diffuse across a cell membrane because they consist of several repeating units of amino acids with positively charged or negatively charged side chains.

Thus, the side chains make these hormones water-loving (hydrophilic), and impassable to the hydrophobic layer of the cell membrane.

the answer is d p: cell, q: organ, r: organ system, s: tissue

d.embryo is the correct one