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Biology, 07.03.2020 02:57 josephmelichar777

In the growth hormone, the receptor binding domain was mapped from amino acids 48-60. In order to determine, which amino acids are involved in its binding to receptor, the following mutations were performed and the binding assay results are listed below. MUTATIONS BINDING ASSAY RESULTS A48 V Yes G46V No A48R Yes H52G Yes G46R No H52D No G46V+H52G No A48R + H52G Noa. What is the role of the amino acid 48? (1 point)b. What is the role of amino acid 52? (1 point)c. What do you conclude from the double mutation G46V+H52G? (1 point)d. What did you learn from the double mutation A48R+H52G? (1 point)e. Which amino acids are important in hormone binding to receptor? (2 points)

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In the growth hormone, the receptor binding domain was mapped from amino acids 48-60. In order to de...
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