A genetic change that caused a certain Hox gene to be expressed along the tip of a vertebrate limb bud instead of farther back helped make possible the evolution of the tetrapod limb. This type of change is illustrative of .

Which of the following factors would not contribute to allopatric speciation? a) a population becomes geographically isolated from the parent population.b) the separated population is small, and genetic drift occurs.c) the isolated population is exposed to different selection pressures than the ancestral population.d) different mutations begin to distinguish the gene pools of the separated populations.e) gene flow between the two populations is extensive.