Restriction enzymes, which are extensively used in molecular biology, are products of bacterial "immune" system. Since bacterial genomes span several million base pairs (E. coli > 4 million bps), and the presence of restriction site within a genome is more than likely, how does a bacteria manage to protect itself from innate REs?

Immune System

Explanation:

In the term of disease by intracellular microscopic organisms, they have the ability and repeated inside phagocytic cells, which causes the circulating antibodies to be distant to intracellular bacteria The natural safe reaction against these microscopic organisms is intervened basically by phagocytes and NK cells  Innate immunity additionally arrives in a protein substance structure, called innate humoral immunity. for example, the body's supplement system and substances called interleukin-1 (which causes fever) and interferon