Enzymes are always changed in the reaction and cannot be used again true or false

False

Explanation:

Enzymes are the biological catalysts that carry out a specific metabolic reaction within the body of living organisms. Further, enzymes are not the reactants and can be used again and again in a biological reaction. They are not used up in the reaction. They also don't change their shapes significantly but slight change takes place that helps in the binding with the substrate.

the answer for apex is "1 and 6"