Biology, 25.03.2020 05:47 simbupls

Suppose a geneticist mutates the gene for the poly(A) tail‑binding protein (PABP) in an eukaryotic cell line. The resulting mutant protein cannot bind to poly(A) tails. What is the effect of the PABP mutation in the cultured cells? Translation will not occur in the cultured cells, because mRNAs will be degraded at a greater rate than normal. Translation will occur in the cultured cells, but the resulting polypeptide will be longer than normal. Transcription will not occur in the cultured cells, because PABP is an essential transcription factor. Transcription will occur in the cultured cells, but the resulting transcript will be longer than normal. Replication will not occur in the cultured cells, because PABP determines the location of the origin of replication.

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Suppose a geneticist mutates the gene for the poly(A) tail‑binding protein (PABP) in an eukaryotic c...

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