Do frame shift mutations cause big or small changes?

you can have just about every answer you can think of

the nitrogen cycle provides nitrogen to the ecosystem from the atmosphere, ground and oceans. nitrogen is an important component of complex molecules such as amino acids and nucleotides, which lead to the creation of proteins and dna, the building blocks of all life. plants absorb nitrogen in the form of ammonium, nitrate ion and, on rare occasions, as amino acids. animals receive nitrogen necessary for biological processes from feeding on living or dead organic matter.

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