Blood flow
The necessity of the normal pattern of blood flow through the heart is graphically illustrated in a pathology known as Transposition of the Great Vessels (TGV). About 4/10,000 infants are born with the congenital heart defect TGV. In this disorder, the origin of the aorta and the pulmonary trunk are switched, however the destinations of these vessels are normal. You may have to do some online research to find a diagram and a description in order to understand this pathology.
1. Select each answer choice that describes the NORMAL sequence of structures through which blood flows, starting with vena cavae. Note that not all structures are listed and that more than one answer may be correct.

a. Bicuspid → right ventricle → aortic valve → pulmonary circulation
b. Right atrium → semilunar valve right ventricle → AV valve → systemic circulation
c. Left atrium → bicuspid → left ventricle → AV valve → systemic circulation
d. Tricuspid → right ventricle → pulmonary valve → pulmonary circulation