Question 14 of 20 A mutation in human ATPase 6, which corresponds to E. coli subunit a, from leucine to arginine at position 156 may allow the movement of protons across the membrane, but not the rotation of the ring of c subunits. How might this possible mechanism affect the function of ATP synthase? Choose two answers. There would be no net effect on the overall function of ATP synthase. There would be an uncoupling of proton translocation and ATP synthesis. The c ring would become uncoupled from the γ and ε subunits. ATP hydrolysis coupled to proton transport out of the matrix would increase. Proton binding to subunit c would be impaired. ATP synthase would remain sensitive to F0 proton conduction inhibitors.

Suppose a point mutation, such as a change from an adenine to a guanine, occurs in the genome of a human sperm cell. the mutation could occur in any region of a gene. the effect of the mutation on the phenotype of the offspring will be determined by where the mutation occurs and its effect on the final gene product. in which of the following scenarios could the mutation alter the phenotype of the offspring? select all of the scenarios that apply the mutation occurs in the promoter and affects the rate of gene transcription. the mutation results in a new, dominant allele the mutation occurs in a portion of an intron not responsible for exon splicing the mutation occurs in a gene that controls development and alters differentiation of a cell type during development. the mutation occurs in a codon and alters the function of the final protein e mutation occurs in a codon, and the amino acid sequence of the final protein is unchanged.