A protein that is normally localized in the cytoplasm has been engineered so that it will be secreted from the cell instead.
Which of the following represents the most likely pathway for the protein after it has been completely synthesized?

A. sER \to Golgi \to secretory vesicle \to environment
B. rER \to secretory vesicle \to Golgi \to environment
C. rER \to Golgi \to sER \to cytoplasm \to environment
D. cytoplasm \to rER \to Golgi \to secretory vesicle \to environment
E. rER \to Golgi \to secretory vesicle \to environment