The pyruvate dehydrogenase (PDH) complex catalyzes the oxidative decarboxylation of pyruvate to acetyl−CoA and CO 2 . CO2. Multiple copies of pyruvate dehydrogenase (E1), dihydrolipoyl transacetylase (E2), and dihydrolipoyl dehydrogenase (E3) along with five cofactors form the PDH complex. Biochemists have studied the PDH complex for decades, in part due to its interesting use of substrate channeling during catalysis. What is the benefit of substrate channeling?
The PDH active site forms in the hydrophobic core of the complex instead of a surface-exposed region.
Reaction progress is not limited by the diffusion constant.
Intermediates of a multistep reaction sequence do not dissociate from the enzyme complex.
The PDH complex sequesters excess substrate to use at later time.
Every intermediate or product made by the PDH complex enters the citric acid cycle as a substrate.

Drag each tile to the correct box. arrange the phases of mitosis in the correct order. 1 (condensation of chromosomes) 2 (separation of chromosomes) 3 (formation of spindle fibers) 4 (alignment of chromosomes in the center of the cell) 5 (pinching of the cell membrane)

Which statements best describe the differences or similarities between a comparative investigation and an experimental investigation? check all that apply. experimental investigations are best for showing cause-and-effect relationships, while comparative investigations do not necessarily show this type of relationship. comparative investigations are often impractical and unrealistic, while experimental investigations are the most practical and realistic kinds of investigations. comparative investigations allow for the use of a wide range of variables but do not have a control group, while experimental investigations involve variables that can be controlled. both experimental investigations and comparative investigations are designed to answer scientific questions. both experimental investigations and comparative investigations focus on making observations rather than collecting new data.

Resperation is a way to release carbon back into the atmosphere