One form of chromatin modification is acetylation, which is known to occur on positively charged histone tail amino acids, thus neutralizing the charge. Based on your understanding of chromatin packaging, we would expect this to (INCREASE/DECREASE/NOT IMPACT) DNA compaction. Which of the following statements best explains your answer?

A. The tails do not interact with the DNA.
B. The tails would now be unable to link together two nucleosomes.
C. The tails would now more tightly interact.

A. The tails do not interact with the DNA

Explanation:

The acetylation refers to the transfer of the acetyl group from Acetyl-CoA to the N-terminal of the histone protein.

Lysine residues (positively charged amino acid) are present at the end of the N-terminal of the histone protein which is neutralized by the acetyl group.

This loses the compaction between the positively charged histone and the negatively charged DNA and the DNA becomes more relaxed. This relaxed state allows the transcription factors to easily bind the DNA and therefore the DNA becomes transcriptionally active.

Thus, Option-A is correct

hey, i believe your answer would be d. sugar ribose and the base uracil. i believe this is the answer, because rna consists of sugar ribose, adenine, guanine, cytosine, and uracil.

your first option is incorrect, because that's dna. where it consists of sugar deoxyribose, adenine, guanine, cytosine and thymine.

your second option is also incorrect, this is because sugar deoxyribose is in dna, and uracil is in rna. these two do not make sense together.

your third option being incorrect, because sugar ribose is in rna, but not the base of thymine. rna consists of uracil, not thymine.

lastly your fourth option being correct! this answer is correct, because both sugar ribose, and the base uracil are in rna! ~

answer is d. sugar ribose and the base uracil.

emerging idea only occurs as a raw idea that could appear out of nowhere. meanwhile, to reach scientific consensus , that idea must be structured and tested over and over again through various experiments. the scientific consensus transforms the raw idea into idea that is more reliable through the process of scientific elimination.