1. Write a paragraph describing whether the statement is correct or incorrect and provide a short explanation (of 3-5 sentences) of why it is correct or incorrect. Your answer should address each component of the statement, demonstrate your understanding of the physiological concepts underlying the statement and be written professionally.
In the kidney, vasoconstriction of the afferent arteriole increases glomerular filtration rate, because hydrostatic pressure in the glomerular capillaries increases (much like putting your thumb over the end of a garden hose increases the pressure and causes the water to exit the hose with greater velocity and travel a greater distance).
2. Write a paragraph of 3-5 sentences describing 1) whether the statement is correct or incorrect and 2) the reasoning for your answer. Feel free to refer to online resources (e. g. Wikipedia) but do not copy or quote any information. Your answer should demonstrate your understanding of the physiological concepts underlying the statement and be professionally written.
Canagliflozin is therapeutically useful for managing type 2 diabetes because this drug decreases the renal clearance of glucose.