A hormone Cascade occurs when

 A hormone can stimulate the release of series of other hormones, the last of which activates a nonendocrine target the cell this is called a hormone cascade pathway. The release of thyroid hormone results from a hormone cascade pathway the hypothalamus, anterior, and thyroid gland.

the cytokine-activated janus kinase (jak)-signal transducer and activator of transcription (stat) pathway has an important role in the control of immune responses. dysregulation of jak-stat signaling is associated with various immune disorders.