The first Clean Water Act of 1972 was significant because it

brain development. a child's brain undergoes an amazing period of development from birth to three—producing more than a million neural connections each second. the development of the brain is influenced by many factors, including a child's relationships, experiences and environment.

explanation:

these muscles maintain the blood pressure in the vessels. the smooth muscles are innervated by nerves of the autonomic nervous system. when the muscles contract, they cause vasoconstriction of the vessels and increase blood pressure. when the muscles relax, they enable vasodilation of the   blood vessels hence reduce blood pressure.